De-Spell is only useful to destroy Geartown/Fortress though, and only on your own turn since it's a normal Spell.
Twister has a bit more use, due to being able to destroy face-up Traps as well, and is a Quick-Play (you can make a surprise play on opponent's turn by Setting it).
I prefer Twister over Double Cyclone. Bad AG players have 3xDouble Cyclone so whenever facing AG, I just dont set any S/T and only special summon to play around the castle. So many times my enemy didnt even summon one Reactor Dragon
Twister is way better, but it seems like most people don't want to open Ultimate Rising because it's too old. So they play double cyclone, galaxy cyclone or even De-Spell.