Divine Wrath can negate his effect of destroying all your other cards, but it won't destroy him. If you have something like Dimensional Prison or Drowning Mirror Force as well, it can be stopped.
From what I understand, the only cards that can protect from the Quintet wiping effect are either Ultra/Super Rare cards or otherwise the limited ones like World legacy clash ?
Is there no Rare or normal Rarity cards that can stop/protect from the wiping ?
Even this is an old thread, even in the time when this card was released, any KoG worthy deck should be able to handle a monster card without destroying it.
Flipping it Face Down with canadia also made its anti destruction effect negated.
To counter Harpie Feather rest, Triamid shuffle, Gagaga Head summoning, thunder dragon hawk after it targets in GY, or force Levianeer to banish only light or only dark.